RCR? What, is that like a new type of PCR or something? Oh, guess not.
Responsible Conduct of Research? Like, ethics? You mean I have to go to a seminar on that? Man, couldn’t we talk about something more interesting, like, I don’t know, cell cultures?
Responsible Conduct of Research is one of those topics that science researchers study in some graduate class, groan about how boring it is, then forget about before continuing on with their lives. Yet taught correctly, RCR is supremely interesting, highly relevant to research today, and (I’ve now realized) incredibly important to learn about. Last Wednesday, Alex’s superbly engaging seminar genuinely sparked my interest in RCR and the politics surrounding science research. During the seminar, we watched the movie “And the Band Played On” with director Robert Spottiswoode (kudos to Alex cause this movie is fantastic! If you haven’t seen it, I HIGHLY recommend it. Seriously. Go rent it RIGHT NOW).
“And the Band Played On” is an adaptation of Randy Shilt’s non-fiction book about the HIV/AIDS epidemic. The movie documents HIV’s rise from discovery to epidemic, especially focusing on the politics behind the government inaction about HIV and the HIV discovery. Of notable importance is…
1. The American government and research’s amazingly slow response to do anything about AIDS, because AIDS was perceived as a “homosexual disease”
2. The unbelievable saga between American scientist Robert Gallo and French scientist Luc Montagnier about who should have credit for the discovery of HIV.
During the movie, I felt hatred for the scientist Robert Gallo and frustration with the politics surrounding AIDS. People were dying from HIV; why did Gallo insist on squabbling with the French for credit over the blood test patent, delaying its production? HIV was spreading throughout the gay population, yet Ronald Reagan still hadn’t said the word HIV in a speech; why wouldn’t he acknowledge the epidemic and give AIDS research funding? HIV was potentially in the blood supply, so why did the blood board turn a blind eye and bleat about needing scientific proof?
Things are better today, right?
Yeah, maybe we think so. Neither I, nor my colleagues, would ever steal research from one another; that would be unethical in the extreme. But the challenges of RCR aren’t simply black and white.
RCR isn’t just about making sure you don’t falsify and steal data. What about if you know that someone else in your lab falsified data? Do you turn them in, accusing your colleague of misconduct? What if the errant person is your superior and you will lose your research job if you turn them over?
What if it seems that someone in your lab falsified the data, but you are unable to solidly prove it? Should you talk to someone about it? Could talking to someone about it destroy your lab’s credibility?
These are hard questions, and when you’re right in the middle of research politics, sometimes it’s harder than one might think to perform up to ethical standards. For most researchers, falsifying data is incredibly unethical, and we would never fabricate results. So the real challenge comes when deciding what to do when others falsify data. Pressure to publish, pressure to work well with your colleagues, pressure to keep your job, and pressure to build a name for your university all push against reporting misconduct. But certainly, science must focus on much more than awards and names, for ideally, humans study science to create accurate, useful empirical knowledge about our world. Perhaps sometimes researchers forget this overarching goal in the glory of a perfect paper, but when science becomes most about the awards than the knowledge, it’s missing a little something. Ensuring the ethical research conduct of our colleagues should be at the forefront of our research ideals. And just as RCR problems are not black and white, neither are the solutions; there are many ways to ensure the ethical conduct.
Alright, time for me to come away from the altar. Now go watch that movie.
Interesting note about the movie title: “And the Band Played On” apparently references the band/orchestra on the Titanic, which supposedly kept playing even as the ship sank to the depths of the ocean. Rather an adept analogy for the politics surrounding the early 1980’s AIDS epidemic Also keep in mind that the movie characters and the dramatization are probably exaggerated and oversimplified. Still, the film is certainly engaging and raises intense questions about RCR.