Just in time for the holiday weekend... and much better than fireworks
I guess I’m a little overdue for a blog update. A little overdue on certain assigned blog topics, too. But we’ll ignore that second part for now…
Anyways, on Friday, experiment finally worked. For the past few weeks, we’d been struggling to get dye loading to work well in our slices (problems with dye solubility and slice health). Friday everything came together and the results (though only proof of experimental design concept; not yet useful in addressing the question of the nature of cortical circuits) were beautiful. Watching neurons light up after stimulation was like watching an incredible fireworks show. Better really, considering that all the flashing was coming from the complex activity of networks of living cells. Incredible. I’ll try to post a few images from the experiment later. Can’t wait to get back to work tomorrow!
HF